17. Auer rods are characteristically seen in:
a) ALL-L2
b) AML-M1
c) AML-M2
d) AML-M3
e) AML-M4
18. M spike in multiple myeloma is usually due
to:
a) IgG
b) Light
chains
c) IgA
d) Heavy
chains
e) Both
light and heavy chains
19. A 60 years old sweeper presents with off
& on diarrhea for the last 6 months which has led to weakness, pallor and
numbness of hands & feet. On examination he is pale. His blood CP reveals
Hb of 6.5 g/dl, TLC 3.0 x 10 3/ul and platelets count of 85,000/cmm. MCV is 110
fl with oval macrocytosis and hypersegmented neutrophils. What is the probable
diagnosis?
a) Iron deficiency anemia
b) Megaloblastic anemia
c) Aplastic anemia
d) Hemolytic anemia
e) Anemia of underlying disorder
20. What investigation would you like to
do next?
a) Serum Ferritin
b) Serum iron, TIBC
c) Bone Marrow examination
d) Hb
electrophoresis
e) Coombs test.
21. The gene for beta globin chain of Hb is
located on chromosome
a) 11
b) 9
c) X
d) 16
e) 1
22. G6PD deficiency is:
a) Inherited as an autosomal dominant disorder
b) Associated with extravascular hemolysis
only
c) X linked
d) Characterized by presence of target cells
in blood
e) Associated with aggravation of symptoms in
hypoxic conditions
23. Sickle cell anemia is
a) Because of a defect in the alpha globin
chain of Hb
b) Associated with intravascular hemolysis
c) Diagnosed on bone marrow examination
d) Diagnosed on Hb electrophoresis
e) Associated with painful crisis resulting
from acute severe vasoconstriction
24. What is the diagnostic test of choice for
iron deficiency anaemia?
a) Peripheral blood film
b) Serum Ferritin levels
c) Serum iron, TIBC
d) Bone Marrow examination
e) Percent Transferrin saturation
25. A young otherwise healthy female presents
with sudden onset of symptoms of anaemia after taking medicine for throat
infection. She is very pale with mild splenomegaly. Her blood CP shows severe
normocytic normochromic anaemia with normal TLC & platelet count.
Spherocytes are also seen. What is the likely cause of her anemia?
a) Autoimmune hemolytic anemia
b) Megaloblastic anemia
c) Iron deficiency anemia
d) PNH
e) Cold haemagglutinin disease
26. What is the diagnostic test for your
provisional diagnosis in above case?
a) Bone marrow examination
b) Urine for hemosidrin
c) Coombs test
d) Hb electrophoresis
e) Iron profile
27. You have diagnosed a
child with beta thalassaemia major. How will you manage this child?
a.
Regular blood
transfusions
b.
Regular blood
transfusion with iron chelation.
c.
Haematinics therapy
d.
Give supportive care
only
e.
Advise bone marrow
transplant immediately
28. Parasite producing iron deficiency is:
a.
Ascaris Lumbricoides
b.
Entrobius vermicularis
c.
Shistosoma haematobium
d.
Entamoeba Histolytica
e.
Ankylostoma Duodenale
29. Pernicious
anaemia is produced due to:
a) Defective absorption of folic acid
b) Defective absorption of Vit B 12 resulting
from deficient R binder
c) Vit B 12 deficiency due to deficiency of
Intrinsic Factor
d)Ileal resection
e) Deficiency of transcobalamine
30. The best source of
folic acid is
a. Milk
b. Eggs
c. Vegetables
d. Meat
e. Animal
liver
31. Bleeding does not
become evident until platelet count is less than:
a. 1,00,000/ul
b. 75,000/ul
c. 50,000/ul
d. 20,000/ul
e. 10,000/ul
32. Individuals
infected by Plasmodium Falciparum are protected against:
a. Thalasemia
b. Iron
deficiency anemia
c. Sickle
cell anemia
d. Megaloblastic
anemia
e. Anemia
of chronic disease
33. Aplastic
anaemia is diagnosed on:
a) Blood counts and reticulocyte count
b) Hb electrophoresis
c) Bone marrow aspirate alone
d) Bone marrow trephine alon
e) Both aspirate and trephine biopsy
17) d
18) b
19) b
20) b
21) a
22) c
23) d
24) b
25) a
26) c
27) b
28) e
29) c
30) d
31) d
32) c
33) d
17) d
18) b
19) b
20) b
21) a
22) c
23) d
24) b
25) a
26) c
27) b
28) e
29) c
30) d
31) d
32) c
33) d
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